Brain Tumor Center
Magnetic Resonance Spectroscopy (MRS)
MRS uses the biochemical make-up of non-water hydrogen protons to evaluate other molecules distributed throughout the brain. For example, MRS can help differentiate between high-grade gliomas and low-grade gliomas. It can detect the differences between a recurrent neoplasm and radiation injury. This technique provides a noninvasive method of characterizing tissue in the brain and providing the unique biochemical information found in the brain tissues.
This is a patient with a history of anaplastic astrocytoma treated with surgery and radiation. An elevation of the choline (Cho) peak relative to the creatine and N-acetyl aspirate (NAA) peaks and the presence of lactate (Lac) are consistent with recurrent tumor. If this area represented radiation necrosis, the peaks of Choline, creatine and NAA would be markedly reduced.